Science & Methods
Peer-reviewed research, methodological insights, and perspectives on clinical evidence
Time Series Forecasting for Critical Systems: Building Reliable Predictions with ARIMAX
A practical guide to ARIMAX modeling for forecasting critical infrastructure, demonstrating how classical statistical methods deliver transparent, validated predictions—illustrated with German gas storage forecasting.
Read →Forest Plots in R with metafor: From Basic to Publication-Ready
A hands-on guide to creating forest plots in R using metafor — from simple plots to publication-ready figures with heterogeneity stats, prediction intervals, and detailed study-level annotations.
Read →Beyond the Standard Model: Multilevel and Multivariate Meta-Analysis for Complex Clinical Evidence
A practical guide to multilevel and multivariate meta-analytic models — handling dependent effect sizes, correlated outcomes, longitudinal data, and arm-based analyses in clinical research.
Read →Meta-Analysis in Clinical Evidence Synthesis: From Effect Sizes to Regulatory Decision-Making
A practical overview of meta-analytic methods for clinical evidence synthesis — covering standard models, effect size measures, heterogeneity, publication bias, and their relevance for regulatory submissions in the medical device and pharmaceutical industry.
Read →ISO 14155 and the Sponsor-Investigator: When the Standard Meets the Ward
ISO 14155:2020 was written with industry sponsors in mind. But what happens when the investigator is also the sponsor? This post examines the real-world burden ISO 14155 places on sponsor-investigators, why most investigator-initiated studies fall short of compliance, and what this means for the relationship between academia and medtech.
Read →Rapid Reviews in Clinical Evidence Synthesis: Speed vs. Precision — A Practitioner's Honest Assessment
Rapid reviews are gaining traction in medical device evidence generation. But what exactly do you trade when you sacrifice Cochrane-grade rigor for speed? This post dissects the method, compares it head-to-head with standard systematic reviews, and tells you when rapid reviews help — and when they can hurt your submission.
Read →Welcome to the MH-Analytics Blog
Welcome to our new blog where we share insights on clinical research, medical device regulations, and best practices in medical writing.
Read →For collaboration inquiries or questions about my research, please get in touch.
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